An EC 1.10.99.* (oxidoreductases acting on diphenols and related substances as donors, other acceptors) inhibitor that interferes with the action of ribosyldihydronicotinamide dehydrogenase (quinone), EC 1.10.99.2.
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | Homo sapiens (human) | Potency | 17.0841 | 1 | 3 |
| 15-lipoxygenase, partial | Homo sapiens (human) | Potency | 0.7943 | 1 | 1 |
| 67.9K protein | Vaccinia virus | Potency | 25.5154 | 1 | 2 |
| activating transcription factor 6 | Homo sapiens (human) | Potency | 3.1164 | 1 | 1 |
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 32.5861 | 1 | 7 |
| AR protein | Homo sapiens (human) | Potency | 21.8585 | 5 | 7 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 48.4412 | 2 | 4 |
| arylsulfatase A | Homo sapiens (human) | Potency | 33.8078 | 1 | 1 |
| ATAD5 protein, partial | Homo sapiens (human) | Potency | 20.5878 | 1 | 1 |
| ATP-dependent phosphofructokinase | Trypanosoma brucei brucei TREU927 | Potency | 6.7456 | 1 | 1 |
| Bloom syndrome protein isoform 1 | Homo sapiens (human) | Potency | 30.0082 | 2 | 4 |
| Cellular tumor antigen p53 | Homo sapiens (human) | Potency | 56.1369 | 2 | 3 |
| cellular tumor antigen p53 isoform a | Homo sapiens (human) | Potency | 1.7560 | 2 | 2 |
| Chain A, 2-oxoglutarate Oxygenase | Homo sapiens (human) | Potency | 10.4876 | 1 | 4 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | Homo sapiens (human) | Potency | 1.6182 | 2 | 7 |
| Chain A, Cruzipain | Trypanosoma cruzi | Potency | 20.9845 | 2 | 4 |
| Chain A, HADH2 protein | Homo sapiens (human) | Potency | 1.8958 | 2 | 5 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | Homo sapiens (human) | Potency | 3.3893 | 2 | 8 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | Giardia intestinalis | Potency | 15.8114 | 1 | 1 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | Homo sapiens (human) | Potency | 26.6514 | 1 | 2 |
| Chain B, HADH2 protein | Homo sapiens (human) | Potency | 1.8958 | 2 | 5 |
| chromobox protein homolog 1 | Homo sapiens (human) | Potency | 44.6684 | 1 | 1 |
| cytochrome P450 2C19 precursor | Homo sapiens (human) | Potency | 15.8489 | 1 | 2 |
| cytochrome P450 2C9 precursor | Homo sapiens (human) | Potency | 11.9464 | 1 | 3 |
| cytochrome P450 2C9, partial | Homo sapiens (human) | Potency | 10.6840 | 1 | 1 |
| cytochrome P450 2D6 | Homo sapiens (human) | Potency | 37.9083 | 1 | 1 |
| cytochrome P450 2D6 isoform 1 | Homo sapiens (human) | Potency | 35.7168 | 1 | 2 |
| cytochrome P450 3A4 isoform 1 | Homo sapiens (human) | Potency | 6.3096 | 2 | 2 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | Homo sapiens (human) | Potency | 10.6840 | 1 | 1 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 25.8727 | 1 | 2 |
| D(1A) dopamine receptor | Homo sapiens (human) | Potency | 4.2880 | 2 | 2 |
| Disintegrin and metalloproteinase domain-containing protein 17 | Homo sapiens (human) | Potency | 31.6228 | 1 | 1 |
| DNA polymerase beta | Homo sapiens (human) | Potency | 0.1995 | 1 | 1 |
| DNA polymerase eta isoform 1 | Homo sapiens (human) | Potency | 0.7943 | 1 | 1 |
| DNA polymerase III, partial | Bacillus subtilis | Potency | 10.6213 | 1 | 1 |
| DNA polymerase iota isoform a (long) | Homo sapiens (human) | Potency | 39.9975 | 1 | 2 |
| DNA polymerase kappa isoform 1 | Homo sapiens (human) | Potency | 0.8592 | 1 | 7 |
| estrogen nuclear receptor alpha | Homo sapiens (human) | Potency | 18.9375 | 6 | 9 |
| estrogen receptor 2 (ER beta) | Homo sapiens (human) | Potency | 25.9324 | 1 | 2 |
| estrogen-related nuclear receptor alpha | Homo sapiens (human) | Potency | 29.7340 | 7 | 12 |
| euchromatic histone-lysine N-methyltransferase 2 | Homo sapiens (human) | Potency | 20.3866 | 1 | 2 |
| EWS/FLI fusion protein | Homo sapiens (human) | Potency | 10.6070 | 4 | 6 |
| flap endonuclease 1 | Homo sapiens (human) | Potency | 14.8554 | 2 | 3 |
| G | Vesicular stomatitis virus | Potency | 10.6840 | 1 | 1 |
| GABA theta subunit | Rattus norvegicus (Norway rat) | Potency | 6.3096 | 1 | 1 |
| galactokinase | Homo sapiens (human) | Potency | 42.1285 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | Potency | 6.3096 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | Potency | 6.3096 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | Potency | 6.3096 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | Rattus norvegicus (Norway rat) | Potency | 6.3096 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | Rattus norvegicus (Norway rat) | Potency | 6.3096 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | Rattus norvegicus (Norway rat) | Potency | 6.3096 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | Rattus norvegicus (Norway rat) | Potency | 6.3096 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-2 | Rattus norvegicus (Norway rat) | Potency | 6.3096 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-3 | Rattus norvegicus (Norway rat) | Potency | 6.3096 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit delta | Rattus norvegicus (Norway rat) | Potency | 6.3096 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | Rattus norvegicus (Norway rat) | Potency | 6.3096 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | Rattus norvegicus (Norway rat) | Potency | 6.3096 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | Rattus norvegicus (Norway rat) | Potency | 6.3096 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | Rattus norvegicus (Norway rat) | Potency | 6.3096 | 1 | 1 |
| Gamma-aminobutyric acid receptor subunit pi | Rattus norvegicus (Norway rat) | Potency | 6.3096 | 1 | 1 |
| GLI family zinc finger 3 | Homo sapiens (human) | Potency | 23.9189 | 2 | 4 |
| GLS protein | Homo sapiens (human) | Potency | 0.4467 | 1 | 1 |
| glucocerebrosidase | Homo sapiens (human) | Potency | 22.9287 | 1 | 4 |
| glucocorticoid receptor [Homo sapiens] | Homo sapiens (human) | Potency | 49.3919 | 1 | 1 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | Homo sapiens (human) | Potency | 50.1187 | 1 | 1 |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | Potency | 12.6457 | 2 | 13 |
| histone deacetylase 9 isoform 3 | Homo sapiens (human) | Potency | 24.5163 | 2 | 4 |
| Histone H2A.x | Cricetulus griseus (Chinese hamster) | Potency | 45.6500 | 2 | 4 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | Homo sapiens (human) | Potency | 22.3872 | 1 | 1 |
| HLA class I histocompatibility antigen, B alpha chain | Homo sapiens (human) | Potency | 10.6840 | 1 | 1 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | Homo sapiens (human) | Potency | 10.0000 | 2 | 2 |
| Inositol hexakisphosphate kinase 1 | Homo sapiens (human) | Potency | 10.6840 | 1 | 2 |
| Inositol monophosphatase 1 | Rattus norvegicus (Norway rat) | Potency | 11.2698 | 1 | 3 |
| Integrin alpha-IIb | Homo sapiens (human) | Potency | 2.5119 | 1 | 1 |
| Integrin beta-3 | Homo sapiens (human) | Potency | 2.5119 | 1 | 1 |
| Interferon beta | Homo sapiens (human) | Potency | 10.6840 | 1 | 1 |
| lamin isoform A-delta10 | Homo sapiens (human) | Potency | 14.1254 | 1 | 1 |
| Luciferase | Photinus pyralis (common eastern firefly) | Potency | 35.7340 | 1 | 2 |
| M-phase phosphoprotein 8 | Homo sapiens (human) | Potency | 39.8107 | 1 | 1 |
| Microtubule-associated protein tau | Homo sapiens (human) | Potency | 8.5505 | 2 | 8 |
| mitogen-activated protein kinase 1 | Homo sapiens (human) | Potency | 35.7168 | 2 | 2 |
| muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | Potency | 11.5574 | 2 | 2 |
| muscleblind-like protein 1 isoform 1 | Homo sapiens (human) | Potency | 28.1838 | 1 | 1 |
| neuropeptide S receptor isoform A | Homo sapiens (human) | Potency | 0.1585 | 1 | 1 |
| NFKB1 protein, partial | Homo sapiens (human) | Potency | 5.6234 | 2 | 2 |
| Nrf2 | Homo sapiens (human) | Potency | 20.5962 | 1 | 1 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 47.6768 | 2 | 4 |
| Parkin | Homo sapiens (human) | Potency | 6.6865 | 2 | 2 |
| peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Homo sapiens (human) | Potency | 2.6855 | 1 | 1 |
| peripheral myelin protein 22 isoform 1 | Homo sapiens (human) | Potency | 47.7548 | 1 | 1 |
| peroxisome proliferator activated receptor gamma | Homo sapiens (human) | Potency | 55.4186 | 1 | 1 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 44.0206 | 1 | 1 |
| phosphoglycerate kinase | Trypanosoma brucei brucei TREU927 | Potency | 7.5686 | 1 | 1 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 60.3510 | 1 | 4 |
| polyunsaturated fatty acid lipoxygenase ALOX12 | Homo sapiens (human) | Potency | 1.0610 | 1 | 2 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | Potency | 14.2191 | 1 | 2 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 65.1393 | 1 | 2 |
| progesterone receptor | Homo sapiens (human) | Potency | 14.5760 | 1 | 2 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 50.3870 | 2 | 4 |
| regulator of G-protein signaling 4 | Homo sapiens (human) | Potency | 11.9173 | 1 | 1 |
| retinoic acid nuclear receptor alpha variant 1 | Homo sapiens (human) | Potency | 28.0806 | 3 | 6 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 15.9743 | 2 | 3 |
| signal transducer and activator of transcription 6, interleukin-4 induced | Homo sapiens (human) | Potency | 2.5119 | 2 | 2 |
| SMAD family member 2 | Homo sapiens (human) | Potency | 15.4845 | 1 | 1 |
| SMAD family member 3 | Homo sapiens (human) | Potency | 15.4845 | 1 | 1 |
| Smad3 | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| survival motor neuron protein isoform d | Homo sapiens (human) | Potency | 35.4813 | 1 | 1 |
| TDP1 protein | Homo sapiens (human) | Potency | 16.5122 | 2 | 10 |
| thioredoxin reductase | Rattus norvegicus (Norway rat) | Potency | 23.7781 | 1 | 1 |
| thyroid hormone receptor beta isoform 2 | Rattus norvegicus (Norway rat) | Potency | 60.8354 | 2 | 3 |
| thyroid hormone receptor beta isoform a | Homo sapiens (human) | Potency | 44.6684 | 1 | 1 |
| thyroid stimulating hormone receptor | Homo sapiens (human) | Potency | 35.2410 | 4 | 7 |
| tyrosine-protein kinase Yes | Homo sapiens (human) | Potency | 15.4103 | 1 | 1 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | Homo sapiens (human) | Potency | 25.0578 | 2 | 2 |
| USP1 protein, partial | Homo sapiens (human) | Potency | 56.2341 | 1 | 1 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | Homo sapiens (human) | Potency | 61.6448 | 1 | 1 |
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|
| 1-deoxy-D-xylulose 5-phosphate reductoisomerase | Escherichia coli K-12 | IC50 | 1.9000 | 1 | 1 |
| 17-beta-hydroxysteroid dehydrogenase type 2 | Homo sapiens (human) | IC50 | 1.5400 | 2 | 2 |
| 3-oxoacyl-acyl-carrier protein reductase | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 5.4000 | 1 | 1 |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | IC50 | 4.0000 | 1 | 1 |
| 5'-nucleotidase | Rattus norvegicus (Norway rat) | Ki | 0.0453 | 1 | 1 |
| 72 kDa type IV collagenase | Homo sapiens (human) | IC50 | 6.6800 | 1 | 1 |
| Acetylcholinesterase | Homo sapiens (human) | Ki | 38.3000 | 1 | 1 |
| Adenosine receptor A1 | Rattus norvegicus (Norway rat) | Ki | 8.9000 | 3 | 3 |
| Adenosine receptor A2a | Rattus norvegicus (Norway rat) | Ki | 5.1250 | 2 | 2 |
| Adenosine receptor A3 | Homo sapiens (human) | Ki | 30.0000 | 1 | 1 |
| ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | Homo sapiens (human) | IC50 | 37.9000 | 1 | 1 |
| Aldo-keto reductase family 1 member A1 | Rattus norvegicus (Norway rat) | IC50 | 2.3200 | 1 | 1 |
| Aldo-keto reductase family 1 member A1 | Sus scrofa (pig) | IC50 | 38.4000 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | Bos taurus (cattle) | IC50 | 17.7540 | 5 | 5 |
| Aldo-keto reductase family 1 member B1 | Homo sapiens (human) | IC50 | 2.2141 | 6 | 6 |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | IC50 | 6.6417 | 5 | 6 |
| Aldo-keto reductase family 1 member B1 | Sus scrofa (pig) | IC50 | 50.1000 | 1 | 1 |
| Aldo-keto reductase family 1 member C21 | Mus musculus (house mouse) | IC50 | 6.9000 | 1 | 1 |
| Aldo-keto reductase family 1 member C21 | Mus musculus (house mouse) | Ki | 11.0000 | 1 | 1 |
| ALK tyrosine kinase receptor | Homo sapiens (human) | IC50 | 3.3200 | 1 | 1 |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | IC50 | 39.9000 | 1 | 2 |
| Alpha-amylase 1A | Homo sapiens (human) | IC50 | 21.4000 | 2 | 2 |
| Alpha-synuclein | Homo sapiens (human) | IC50 | 20.0000 | 1 | 1 |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | IC50 | 2.6200 | 2 | 2 |
| Amine oxidase [flavin-containing] A | Bos taurus (cattle) | IC50 | 0.0100 | 1 | 1 |
| Amine oxidase [flavin-containing] B | Bos taurus (cattle) | IC50 | 20.0000 | 1 | 1 |
| Amine oxidase [flavin-containing] B | Homo sapiens (human) | IC50 | 64.3300 | 2 | 2 |
| Amyloid-beta precursor protein | Homo sapiens (human) | IC50 | 40.7850 | 4 | 4 |
| Anthrax toxin receptor 2 | Homo sapiens (human) | IC50 | 300.0000 | 1 | 1 |
| Arginase | Leishmania amazonensis | IC50 | 4.0000 | 1 | 1 |
| Aromatase | Homo sapiens (human) | IC50 | 6.0060 | 2 | 2 |
| ATP-binding cassette sub-family C member 3 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | IC50 | 52.5000 | 1 | 1 |
| Aurora kinase B | Homo sapiens (human) | IC50 | 2.4350 | 2 | 2 |
| B2 bradykinin receptor | Cavia porcellus (domestic guinea pig) | IC50 | 4.0000 | 2 | 2 |
| Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein) | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 1.5000 | 1 | 1 |
| Beta-lactamase | Enterobacter cloacae | IC50 | 269.6667 | 3 | 3 |
| Beta-lactamase | Escherichia coli K-12 | IC50 | 58.0000 | 4 | 4 |
| Beta-secretase 1 | Homo sapiens (human) | IC50 | 7.6400 | 3 | 3 |
| Beta-secretase 1 | Homo sapiens (human) | Ki | 14.0000 | 1 | 1 |
| Bifunctional epoxide hydrolase 2 | Homo sapiens (human) | IC50 | 20.2700 | 2 | 2 |
| Bile salt export pump | Homo sapiens (human) | IC50 | 134.0000 | 2 | 2 |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | IC50 | 7.2500 | 2 | 2 |
| C-C chemokine receptor type 4 | Homo sapiens (human) | IC50 | 47.2409 | 3 | 6 |
| C-X-C chemokine receptor type 1 | Homo sapiens (human) | IC50 | 35.3780 | 2 | 4 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B | Rattus norvegicus (Norway rat) | IC50 | 275.0000 | 1 | 1 |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C | Rattus norvegicus (Norway rat) | IC50 | 275.0000 | 1 | 1 |
| Calcium/calmodulin-dependent protein kinase type II subunit beta | Homo sapiens (human) | IC50 | 3.0000 | 1 | 1 |
| Calmodulin-1 | Homo sapiens (human) | IC50 | 12.9700 | 1 | 1 |
| Canalicular multispecific organic anion transporter 1 | Homo sapiens (human) | IC50 | 133.0000 | 1 | 1 |
| Carbonic anhydrase 1 | Homo sapiens (human) | Ki | 29.9138 | 4 | 8 |
| Carbonic anhydrase 12 | Homo sapiens (human) | Ki | 9.3900 | 1 | 1 |
| Carbonic anhydrase 13 | Mus musculus (house mouse) | Ki | 9.0300 | 1 | 1 |
| Carbonic anhydrase 14 | Homo sapiens (human) | Ki | 5.4100 | 1 | 1 |
| Carbonic anhydrase 2 | Homo sapiens (human) | Ki | 29.8962 | 4 | 8 |
| Carbonic anhydrase 3 | Bos taurus (cattle) | Ki | 6.5260 | 2 | 5 |
| Carbonic anhydrase 3 | Homo sapiens (human) | Ki | 8.1000 | 1 | 1 |
| Carbonic anhydrase 4 | Homo sapiens (human) | Ki | 6.7533 | 3 | 6 |
| Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | Ki | 6.8100 | 1 | 1 |
| Carbonic anhydrase 5B, mitochondrial | Homo sapiens (human) | Ki | 11.9000 | 1 | 1 |
| Carbonic anhydrase 6 | Homo sapiens (human) | Ki | 4.9500 | 2 | 2 |
| Carbonic anhydrase 7 | Homo sapiens (human) | Ki | 4.8400 | 1 | 1 |
| Carbonic anhydrase 9 | Homo sapiens (human) | Ki | 7.0000 | 1 | 1 |
| Casein kinase II subunit alpha | Homo sapiens (human) | IC50 | 1.6500 | 5 | 5 |
| Casein kinase II subunit alpha | Homo sapiens (human) | Ki | 1.1800 | 4 | 4 |
| Casein kinase II subunit alpha 3 | Homo sapiens (human) | IC50 | 0.5500 | 1 | 1 |
| Casein kinase II subunit alpha 3 | Homo sapiens (human) | Ki | 1.1800 | 1 | 1 |
| Casein kinase II subunit alpha' | Homo sapiens (human) | IC50 | 1.6500 | 5 | 5 |
| Casein kinase II subunit alpha' | Homo sapiens (human) | Ki | 1.1800 | 1 | 1 |
| Casein kinase II subunit beta | Homo sapiens (human) | IC50 | 1.6500 | 5 | 5 |
| Casein kinase II subunit beta | Homo sapiens (human) | Ki | 1.1800 | 1 | 1 |
| Cationic trypsin | Bos taurus (cattle) | IC50 | 24.4200 | 2 | 5 |
| cGMP-dependent 3',5'-cyclic phosphodiesterase | Rattus norvegicus (Norway rat) | IC50 | 81.3000 | 1 | 1 |
| Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase | Helicobacter pylori | Ki | 12.7000 | 1 | 3 |
| Chain A, APH(2')-Id | Enterococcus casseliflavus | Ki | 25.1000 | 1 | 1 |
| Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase | Helicobacter pylori | Ki | 12.7000 | 1 | 3 |
| Chymotrypsin-C | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Chymotrypsin-like elastase family member 1 | Sus scrofa (pig) | IC50 | 28.7500 | 1 | 4 |
| Chymotrypsinogen A | Bos taurus (cattle) | IC50 | 292.5000 | 2 | 2 |
| Chymotrypsinogen B | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Coagulation factor X | Homo sapiens (human) | Ki | 2.8533 | 3 | 3 |
| Coagulation factor XII | Homo sapiens (human) | IC50 | 33.0000 | 1 | 1 |
| Collagenase 3 | Homo sapiens (human) | IC50 | 8.4600 | 1 | 1 |
| Cyclin homolog | Herpesvirus saimiri (strain 11) | IC50 | 31.2750 | 1 | 4 |
| Cyclin-dependent kinase 1 | Homo sapiens (human) | IC50 | 28.8625 | 4 | 4 |
| Cyclin-dependent kinase 1 | Oryzias latipes (Japanese medaka) | IC50 | 31.2750 | 1 | 4 |
| Cyclin-dependent kinase 2 | Homo sapiens (human) | IC50 | 40.0000 | 1 | 1 |
| Cyclin-dependent kinase 4 | Homo sapiens (human) | IC50 | 61.0000 | 1 | 1 |
| Cyclin-dependent kinase 5 activator 1 | Homo sapiens (human) | IC50 | 29.6200 | 2 | 5 |
| Cyclin-dependent kinase 6 | Homo sapiens (human) | IC50 | 30.0200 | 2 | 5 |
| Cyclin-dependent-like kinase 5 | Homo sapiens (human) | IC50 | 29.6200 | 2 | 5 |
| Cytochrome P450 11B1, mitochondrial | Rattus norvegicus (Norway rat) | IC50 | 50.0000 | 1 | 1 |
| Cytochrome P450 1A1 | Homo sapiens (human) | IC50 | 8.4364 | 5 | 5 |
| Cytochrome P450 1A1 | Homo sapiens (human) | Ki | 0.6600 | 1 | 1 |
| Cytochrome P450 1A2 | Homo sapiens (human) | IC50 | 14.6990 | 3 | 3 |
| Cytochrome P450 1B1 | Homo sapiens (human) | IC50 | 1.1108 | 5 | 5 |
| Cytochrome P450 1B1 | Homo sapiens (human) | Ki | 0.0230 | 2 | 2 |
| Cytochrome P450 2C8 | Homo sapiens (human) | IC50 | 13.5000 | 2 | 2 |
| Cytochrome P450 2C9 | Homo sapiens (human) | Ki | 27.0000 | 1 | 1 |
| Cytochrome P450 2D6 | Homo sapiens (human) | IC50 | 20.0000 | 2 | 2 |
| Cytochrome P450 3A4 | Homo sapiens (human) | IC50 | 15.6667 | 3 | 3 |
| Cytosol aminopeptidase | Sus scrofa (pig) | IC50 | 34.3000 | 1 | 1 |
| D(4) dopamine receptor | Homo sapiens (human) | Ki | 7.8460 | 1 | 1 |
| Death-associated protein kinase 1 | Homo sapiens (human) | IC50 | 8.9000 | 1 | 1 |
| Dipeptidyl peptidase 3 | Homo sapiens (human) | IC50 | 74.1000 | 1 | 1 |
| Dipeptidyl peptidase 4 | Homo sapiens (human) | IC50 | 66.4600 | 2 | 2 |
| Dual specificity mitogen-activated protein kinase kinase 1 | Homo sapiens (human) | IC50 | 10.0000 | 1 | 1 |
| ELAV-like protein 1 | Homo sapiens (human) | IC50 | 1.4000 | 1 | 1 |
| ELAV-like protein 3 | Homo sapiens (human) | IC50 | 1.8000 | 1 | 1 |
| Enoyl-[acyl-carrier-protein] reductase [NADH] FabI | Escherichia coli K-12 | IC50 | 20.0000 | 1 | 1 |
| Enoyl-acyl-carrier protein reductase | Plasmodium falciparum (malaria parasite P. falciparum) | IC50 | 1.8333 | 3 | 3 |
| Enoyl-acyl-carrier protein reductase | Plasmodium falciparum (malaria parasite P. falciparum) | Ki | 0.5283 | 3 | 3 |
| Epidermal growth factor receptor | Homo sapiens (human) | IC50 | 68.6000 | 3 | 3 |
| Epoxide hydrolase 1 | Homo sapiens (human) | IC50 | 7.0000 | 1 | 1 |
| Focal adhesion kinase 1 | Homo sapiens (human) | IC50 | 1.2000 | 1 | 1 |
| G-protein coupled receptor 35 | Homo sapiens (human) | IC50 | 15.4000 | 1 | 1 |
| G1/S-specific cyclin-D1 | Homo sapiens (human) | IC50 | 61.0000 | 1 | 1 |
| G2/mitotic-specific cyclin-B | Marthasterias glacialis (spiny starfish) | IC50 | 31.2750 | 1 | 4 |
| G2/mitotic-specific cyclin-B1 | Homo sapiens (human) | IC50 | 38.3333 | 3 | 3 |
| G2/mitotic-specific cyclin-B2 | Homo sapiens (human) | IC50 | 75.0000 | 1 | 1 |
| G2/mitotic-specific cyclin-B3 | Homo sapiens (human) | IC50 | 75.0000 | 1 | 1 |
| glucose-6-phosphate dehydrogenase | Leuconostoc mesenteroides | IC50 | 25.0000 | 1 | 1 |
| Glutathione reductase | Saccharomyces cerevisiae S288C | IC50 | 48.8000 | 1 | 1 |
| Glutathione reductase, mitochondrial | Homo sapiens (human) | IC50 | 218.0000 | 1 | 1 |
| Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | Trypanosoma cruzi | IC50 | 142.0000 | 1 | 1 |
| Glycogen phosphorylase, liver form | Homo sapiens (human) | IC50 | 4.8000 | 1 | 1 |
| Glycogen synthase kinase-3 alpha | Homo sapiens (human) | IC50 | 2.1000 | 1 | 1 |
| Glycogen synthase kinase-3 beta | Homo sapiens (human) | IC50 | 2.1000 | 1 | 1 |
| Glycogen synthase kinase-3 beta | Rattus norvegicus (Norway rat) | IC50 | 31.2750 | 1 | 4 |
| Heat shock factor protein 1 | Homo sapiens (human) | IC50 | 50.0000 | 1 | 1 |
| Hepatocyte growth factor receptor | Homo sapiens (human) | IC50 | 0.5800 | 1 | 1 |
| hexokinase | Trypanosoma brucei brucei TREU927 | IC50 | 22.3780 | 1 | 1 |
| Hypoxia-inducible factor 1-alpha inhibitor | Homo sapiens (human) | IC50 | 10.2000 | 1 | 1 |
| Inositol hexakisphosphate kinase 2 | Homo sapiens (human) | IC50 | 0.7000 | 1 | 1 |
| Inositol polyphosphate multikinase | Homo sapiens (human) | IC50 | 2.3000 | 1 | 1 |
| Insulin-like growth factor 1 receptor | Homo sapiens (human) | IC50 | 0.3000 | 1 | 1 |
| Integrase | Human immunodeficiency virus 1 | IC50 | 13.1600 | 5 | 5 |
| Interstitial collagenase | Homo sapiens (human) | IC50 | 1.4900 | 1 | 1 |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | IC50 | 1.0000 | 1 | 1 |
| Lactoperoxidase | Bos taurus (cattle) | IC50 | 6.1000 | 1 | 1 |
| Lactoylglutathione lyase | Homo sapiens (human) | IC50 | 3.2000 | 1 | 1 |
| Lactoylglutathione lyase | Homo sapiens (human) | Ki | 15.1356 | 1 | 1 |
| Lysine-specific histone demethylase 1A | Homo sapiens (human) | IC50 | 1.2600 | 1 | 1 |
| Lysosomal alpha-glucosidase | Homo sapiens (human) | IC50 | 7.8000 | 1 | 1 |
| Macrophage metalloelastase | Homo sapiens (human) | IC50 | 10.2300 | 1 | 1 |
| Malate dehydrogenase | Thermus thermophilus | IC50 | 6.0000 | 1 | 1 |
| Maltase-glucoamylase, intestinal | Homo sapiens (human) | IC50 | 9.3000 | 2 | 2 |
| Matrix metalloproteinase-9 | Homo sapiens (human) | IC50 | 0.8919 | 2 | 2 |
| Mitogen-activated protein kinase 10 | Homo sapiens (human) | IC50 | 2.8800 | 1 | 2 |
| Mitogen-activated protein kinase 14 | Homo sapiens (human) | IC50 | 2.8800 | 1 | 2 |
| Monocarboxylate transporter 1 | Rattus norvegicus (Norway rat) | IC50 | 14.0000 | 1 | 1 |
| Monocarboxylate transporter 2 | Rattus norvegicus (Norway rat) | IC50 | 5.0000 | 1 | 1 |
| Multidrug and toxin extrusion protein 1 | Homo sapiens (human) | IC50 | 8.1000 | 1 | 1 |
| Multidrug and toxin extrusion protein 2 | Homo sapiens (human) | IC50 | 25.3000 | 1 | 1 |
| Multidrug resistance-associated protein 1 | Homo sapiens (human) | Ki | 5.2500 | 2 | 2 |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | IC50 | 20.8000 | 1 | 1 |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | IC50 | 10.0000 | 1 | 1 |
| Myeloperoxidase | Homo sapiens (human) | IC50 | 1.6975 | 4 | 4 |
| NADPH oxidase 4 | Homo sapiens (human) | IC50 | 0.6800 | 1 | 1 |
| Neuraminidase | Influenza A virus (A/Puerto Rico/8/1934(H1N1)) | IC50 | 7.7500 | 1 | 1 |
| Neuraminidase | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | IC50 | 53.9250 | 4 | 4 |
| Neuraminidase | Influenza A virus (A/Wilson-Smith/1933(H1N1)) | Ki | 3.8000 | 1 | 1 |
| Neutrophil elastase | Homo sapiens (human) | IC50 | 18.3390 | 2 | 2 |
| Neutrophil elastase | Homo sapiens (human) | Ki | 11.9000 | 1 | 1 |
| Nitric oxide synthase, inducible | Mus musculus (house mouse) | IC50 | 16.4000 | 1 | 1 |
| NUAK family SNF1-like kinase 1 | Homo sapiens (human) | IC50 | 5.0900 | 1 | 1 |
| Oligo-1,6-glucosidase IMA1 | Saccharomyces cerevisiae S288C | IC50 | 530.0000 | 1 | 1 |
| Pancreatic triacylglycerol lipase | Sus scrofa (pig) | IC50 | 70.0000 | 1 | 1 |
| Phosphatidylinositol 3-kinase regulatory subunit alpha | Homo sapiens (human) | IC50 | 3.8000 | 1 | 1 |
| Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | Homo sapiens (human) | IC50 | 8.7950 | 2 | 2 |
| Phosphodiesterase | Rattus norvegicus (Norway rat) | IC50 | 275.0000 | 1 | 1 |
| Phospholipase A2 | Homo sapiens (human) | IC50 | 2.0000 | 1 | 1 |
| Plasminogen | Homo sapiens (human) | Ki | 1.6950 | 1 | 1 |
| Polyphenol oxidase 2 | Agaricus bisporus | IC50 | 135.5000 | 2 | 2 |
| Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | IC50 | 6.9580 | 5 | 5 |
| Polyunsaturated fatty acid 5-lipoxygenase | Rattus norvegicus (Norway rat) | IC50 | 1.9500 | 6 | 6 |
| Polyunsaturated fatty acid lipoxygenase ALOX12 | Homo sapiens (human) | IC50 | 0.4400 | 1 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Homo sapiens (human) | IC50 | 2.2000 | 1 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | IC50 | 18.7150 | 2 | 2 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | Homo sapiens (human) | IC50 | 100.0000 | 1 | 1 |
| Probable maltase-glucoamylase 2 | Homo sapiens (human) | IC50 | 7.8000 | 1 | 1 |
| Prolyl endopeptidase | Homo sapiens (human) | IC50 | 13.0000 | 1 | 1 |
| Prostaglandin G/H synthase 1 | Rattus norvegicus (Norway rat) | IC50 | 50.0000 | 2 | 2 |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | IC50 | 28.6000 | 1 | 1 |
| Prostaglandin G/H synthase 2 | Rattus norvegicus (Norway rat) | IC50 | 50.0000 | 2 | 2 |
| Proteasome subunit beta type-5 | Homo sapiens (human) | IC50 | 2.7500 | 2 | 2 |
| Protein E6 | Human papillomavirus 16 | IC50 | 20.0000 | 1 | 1 |
| Prothrombin | Homo sapiens (human) | IC50 | 2.2539 | 14 | 14 |
| Prothrombin | Homo sapiens (human) | Ki | 0.0050 | 7 | 7 |
| Prothrombin | Bos taurus (cattle) | IC50 | 28.7500 | 1 | 4 |
| Proto-oncogene tyrosine-protein kinase receptor Ret | Homo sapiens (human) | IC50 | 78.1000 | 1 | 1 |
| Proto-oncogene tyrosine-protein kinase Src | Homo sapiens (human) | IC50 | 7.5600 | 2 | 2 |
| RAC-alpha serine/threonine-protein kinase | Homo sapiens (human) | IC50 | 5.3900 | 1 | 1 |
| Receptor-type tyrosine-protein kinase FLT3 | Homo sapiens (human) | IC50 | 0.5900 | 1 | 1 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | IC50 | 23.8000 | 1 | 1 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | IC50 | 26.4250 | 4 | 4 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | Ki | 7.4000 | 1 | 1 |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | Ki | 7.4000 | 1 | 1 |
| Ribosyldihydronicotinamide dehydrogenase [quinone] | Homo sapiens (human) | IC50 | 10.5000 | 2 | 2 |
| Ribosyldihydronicotinamide dehydrogenase [quinone] | Homo sapiens (human) | Ki | 60.0000 | 1 | 1 |
| Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | Oryctolagus cuniculus (rabbit) | IC50 | 9.0000 | 1 | 1 |
| Seed linoleate 13S-lipoxygenase-1 | Glycine max (soybean) | Ki | 106.7000 | 1 | 1 |
| Serine protease hepsin | Homo sapiens (human) | Ki | 0.8350 | 1 | 1 |
| Serine/threonine-protein kinase B-raf | Homo sapiens (human) | IC50 | 7.5890 | 1 | 1 |
| Serine/threonine-protein kinase N1 | Homo sapiens (human) | IC50 | 5.8000 | 1 | 1 |
| Serine/threonine-protein kinase Nek2 | Homo sapiens (human) | IC50 | 5.7300 | 1 | 1 |
| Serine/threonine-protein kinase Nek6 | Homo sapiens (human) | IC50 | 4.2300 | 1 | 1 |
| Serine/threonine-protein kinase pim-1 | Homo sapiens (human) | IC50 | 0.7686 | 5 | 5 |
| Serine/threonine-protein kinase PLK1 | Homo sapiens (human) | IC50 | 34.8750 | 2 | 2 |
| Short transient receptor potential channel 5 | Homo sapiens (human) | IC50 | 6.5000 | 1 | 1 |
| Sialidase | Clostridium perfringens | IC50 | 9.9200 | 5 | 5 |
| Sialidase-2 | Homo sapiens (human) | IC50 | 160.0000 | 1 | 1 |
| Sodium- and chloride-dependent betaine transporter | Rattus norvegicus (Norway rat) | IC50 | 50.0000 | 1 | 1 |
| Sodium- and chloride-dependent GABA transporter 1 | Rattus norvegicus (Norway rat) | IC50 | 50.0000 | 1 | 1 |
| Sodium- and chloride-dependent GABA transporter 2 | Rattus norvegicus (Norway rat) | IC50 | 50.0000 | 1 | 1 |
| Sodium- and chloride-dependent GABA transporter 3 | Rattus norvegicus (Norway rat) | IC50 | 50.0000 | 1 | 1 |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | IC50 | 20.0000 | 1 | 1 |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | IC50 | 1.0000 | 1 | 1 |
| Solute carrier family 2, facilitated glucose transporter member 2 | Homo sapiens (human) | IC50 | 12.0000 | 2 | 2 |
| Solute carrier family 2, facilitated glucose transporter member 4 | Rattus norvegicus (Norway rat) | Ki | 16.0000 | 1 | 1 |
| Solute carrier family 22 member 2 | Homo sapiens (human) | IC50 | 4.7000 | 1 | 1 |
| Sorbitol dehydrogenase | Homo sapiens (human) | IC50 | 106.3000 | 2 | 2 |
| Stromelysin-1 | Homo sapiens (human) | IC50 | 5.5700 | 1 | 1 |
| Substance-K receptor | Cavia porcellus (domestic guinea pig) | IC50 | 58.4000 | 1 | 1 |
| Substance-P receptor | Cavia porcellus (domestic guinea pig) | IC50 | 58.4000 | 1 | 1 |
| Sucrase-isomaltase, intestinal | Homo sapiens (human) | IC50 | 7.8000 | 1 | 1 |
| Tissue-type plasminogen activator | Homo sapiens (human) | Ki | 45.3600 | 1 | 1 |
| Trypsin-1 | Homo sapiens (human) | IC50 | 15.4000 | 1 | 1 |
| Trypsin-1 | Homo sapiens (human) | Ki | 0.0502 | 2 | 2 |
| Trypsin-2 | Homo sapiens (human) | IC50 | 15.4000 | 1 | 1 |
| Trypsin-2 | Homo sapiens (human) | Ki | 0.0502 | 2 | 2 |
| Trypsin-3 | Homo sapiens (human) | IC50 | 15.4000 | 1 | 1 |
| Trypsin-3 | Homo sapiens (human) | Ki | 0.0502 | 2 | 2 |
| Tyrosinase | Homo sapiens (human) | IC50 | 44.3800 | 1 | 1 |
| Tyrosine-protein kinase Lck | Homo sapiens (human) | IC50 | 13.0000 | 2 | 2 |
| Tyrosine-protein kinase receptor UFO | Homo sapiens (human) | IC50 | 0.9600 | 1 | 1 |
| Tyrosine-protein kinase SYK | Homo sapiens (human) | IC50 | 20.0000 | 1 | 1 |
| Tyrosine-protein kinase Yes | Homo sapiens (human) | Ki | 0.4720 | 1 | 1 |
| Tyrosine-protein phosphatase non-receptor type 1 | Homo sapiens (human) | IC50 | 23.3000 | 2 | 2 |
| Urease subunit alpha | Helicobacter pylori 26695 | IC50 | 11.1333 | 3 | 3 |
| Urease subunit alpha | Helicobacter pylori 26695 | Ki | 9.3400 | 1 | 1 |
| Urease subunit beta | Helicobacter pylori 26695 | IC50 | 11.1333 | 3 | 3 |
| Urease subunit beta | Helicobacter pylori 26695 | Ki | 9.3400 | 1 | 1 |
| Urokinase-type plasminogen activator | Homo sapiens (human) | IC50 | 25.4200 | 2 | 5 |
| Vascular endothelial growth factor receptor 2 | Homo sapiens (human) | IC50 | 0.9700 | 2 | 2 |
| Vasopressin V2 receptor | Homo sapiens (human) | IC50 | 20.3282 | 3 | 6 |
| Vitamin K-dependent protein C | Homo sapiens (human) | Ki | 20.9300 | 1 | 1 |
| Xanthine dehydrogenase/oxidase | Bos taurus (cattle) | IC50 | 31.9000 | 1 | 1 |
| Xanthine dehydrogenase/oxidase | Homo sapiens (human) | IC50 | 3.0400 | 3 | 3 |
| Xanthine dehydrogenase/oxidase | Bos taurus (cattle) | Ki | 1.2000 | 1 | 1 |
| Xanthine dehydrogenase/oxidase | Homo sapiens (human) | Ki | 0.2800 | 1 | 1 |